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Exposure of male albino rats to temperatures of 0 to 2° C. for two weeks resulted in osteoporosis of alveolar bone, characterized by decreased osteoblastic activity and periodontal membrane changes consisting of decreased cellularity and granularity of the collagen. With continued exposure, the changes in the periodontium diminished in severity. There was evidence of changes after four weeks, but after four months the periodontium returned to normal.
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☆This report is from an investigation supported by the United States Public Health Service under Contract 646.
☆An abstract of this report was presented at the thirty-seventh annual meeting of the International Association for Dental Research in San Francisco, California, March 19–22, 1959.
© 1959 Published by Elsevier Inc.