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Research Article| Volume 12, ISSUE 9, P1141-1146, September 1959

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The inhibitory action of stimulated whole saliva on the in vitro growth of clostridium tetani

  • Henry A. Bartels
    Affiliations
    From the Department of Microbiology, Institute for Dental Research, College of Dentistry, New York University. New York, N.Y. USA

    The Murray and Leonie Guggenheim Foundation, Institute for Dental Research, College of Dentistry, New York University. New York, N.Y. USA
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  • Harry Blechman
    Affiliations
    From the Department of Microbiology, Institute for Dental Research, College of Dentistry, New York University. New York, N.Y. USA

    The Murray and Leonie Guggenheim Foundation, Institute for Dental Research, College of Dentistry, New York University. New York, N.Y. USA
    Search for articles by this author
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      Abstract

      Freshly stimulated saliva exhibits an inhibitory action toward the tetanus bacillus. The factor is distinct from lysozyme and is not filterable through the Seitz filter. It appears to be associated with the oral microbiota. Exposure of tetanus spores to the oral microbiota does not destroy them but does inhibit their germination.
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