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Abstract
The therapeutic effectiveness of Protamide was investigated in a series of twelve
cases of severe herpes simplex seen in dental practice. Injections (1.3 ml.) were
administered intramuscularly on two successive days. Excellent results were obtained
in most patients and no side effects were seen. It appears that if the drug is going
to be effective, relief should be obtained following the first two injections. Protamide
is sufficiently effective to warrant its use in patients with severe herpes simplex.
In the twelve cases studied, ten patients responded favorably and two showed no response.
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References
- Treatment of Herpes Zoster With Protamide.U. S. Armed Forces M. J. 1950; 1: 1045
- Herpes Zoster: Its Treatment With Protamide.New York J. Med. 1952; 52: 706
- A New Treatment for Chickenpox and Other Virus Diseases: Preliminary Report.Ohio M. J. 1951; 47: 44
- Clinical Evaluation of Protamide in Sensory Nerve Root Inflammation and Allied Conditions.Northwest Med. 1955; 54: 1249
- Treatment of Neuritis With Protamide.New York Med. 1952; 8: 16
- Pharmacologic Study of Protamide.Urol. & Cutan. Rev. 1944; 48: 378
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© 1961 Published by Elsevier Inc.
