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Research Article| Volume 14, ISSUE 12, P1501-1509, December 1961

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Metastasis of bronchogenic carcinoma to the mandible

Report of a case
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      Abstract

      A rare instance of metastasis to the mandible from a primary bronchogenic carcinoma has been described. As a forerunner to the fatal course of the disease, symptoms mimicking a “gumboil” caused an investigation sequence which led to a diagnosis of lung cancer. The neoplastic cells invading mandibular bone were identified as mucus-secreting cells of an adenocarcinoma. Roentgenograms revealed the existence of an asymptomatic primary lung tumor.
      The frequency of metastatic bone invasion in bronchogenic carcinoma was reported and compared with bone metastases of other primary carcinomas. Radiographic features of the metastatic bone lesions, as well as the identification of cell types and their frequency in primary lung cancer and in metastases to bone, were discussed.
      With the rising incidence of lung cancer, metastatic invasion from bronchogenic carcinoma must be considered in the differential diagnosis of all osteolytic lesions found in the jaws.
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