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Abstract
Povidone (polyvinylpyrrolidone)-iodine is an effective germicide. High dilutions are
active in destroying, within fifteen seconds, the organisms commonly found in the
mouth. It is effective in higher dilutions than the stock commercial preparations
of the other common antiseptics studied.
In 10 per cent aqueous solution, the antiseptic properties of polyvinylpyrrolidone
iodine have been retained for more than one year. High dilutions, however, should
be freshly prepared; color loss is accompanied by a weakening of germicidal activity.
When povidone-iodine is used to prepare the oral mucosa for local anesthetic injection
prior to dental procedures, the hazard of direct bacterial infection is removed almost
completely. In the present study polyvinylpyrrolidone iodine was used in ninety-nine
patients who received a total of 115 injections, and in only five instances were bacteria
recovered from the injection needle.
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References
- PVP-Iodine: History, Toxicity, and Therapeutic Uses.J. Internat. Coll. Surgeons. 1956; 25: 727-734
- Effect of Polyvinylpyrrolidone in Obstetrical Cases.Surg. Gynec. & Obst. 1953; 96: 581-583
- Polyvinylpyrrolidone in Severe Burn.Shock. Surg. Gynec. & Obst. 1953; 97: 39-44
- Polyvinylpyrrolidone in Acute Traumatic and Hemorrhagic.Shock. Surg. Gynec. & Obst. 1953; 97: 361-367
- Polyvinylpyrrolidone in the Treatment of Traumatic and Hemmorhagic Shock and Severe Burns.New York J. Med. 1954; 54: 652-658
- Microbiologic Hazards of Local Dental Anesthesia. I. A State-wide Survey of Procedures in Common Practice.J. Am. Dent. A. 1958; 56: 508-513
- Microbiologic Hazards of Local Dental Anesthesia. II. Pilot Study of Involuntary Aspiration of Bacteria Into Hypodermic Needles and Anesthetic Cartridges After Injection.J. Am. Dent. A. 1958; 57: 657-664
Article info
Footnotes
☆This investigation was reported in part at the Fifty-eighth General meeting of the Society of American Bacteriologists, Chicago, Illinois, April 27 to May 1, 1958.
Identification
Copyright
© 1961 Published by Elsevier Inc.
