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Povidone (polyvinylpyrrolidone)-iodine is an effective germicide. High dilutions are active in destroying, within fifteen seconds, the organisms commonly found in the mouth. It is effective in higher dilutions than the stock commercial preparations of the other common antiseptics studied.
In 10 per cent aqueous solution, the antiseptic properties of polyvinylpyrrolidone iodine have been retained for more than one year. High dilutions, however, should be freshly prepared; color loss is accompanied by a weakening of germicidal activity.
When povidone-iodine is used to prepare the oral mucosa for local anesthetic injection prior to dental procedures, the hazard of direct bacterial infection is removed almost completely. In the present study polyvinylpyrrolidone iodine was used in ninety-nine patients who received a total of 115 injections, and in only five instances were bacteria recovered from the injection needle.
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☆This investigation was reported in part at the Fifty-eighth General meeting of the Society of American Bacteriologists, Chicago, Illinois, April 27 to May 1, 1958.
© 1961 Published by Elsevier Inc.