Research Article| Volume 14, ISSUE 9, P1046-1052, September 1961

Preliminary study of the effects of a strontium chloride dentifrice for the control of hypersensitive teeth

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      A 10 per cent concentration of strontium chloride, in a neutral, compatible dentifrice base which releases strontium ions when in contact with water, has been demonstrated to be useful in controlling the pain arising from hypersensitive cementum in about 75 per cent of the cases studied.
      I know of no contraindications to the use of strontium chloride for the intended purpose, since as it is used it is apparently nonirritating, nonallergenic, and nontoxic. Its incorporation into a dentifrice seems to make possible, for the first time, a rational, safe, effective therapy that can be used in a daily regimen by the patient suffering from hypersensitive cementum. It is suggested that the results obtained in this study may provide an incentive for additional histologic and laboratory studies on the mechanism of action of water-soluble strontium as well as further clinical evaluations of these compounds and of dentifrices containing them.
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