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Oral thrush, or acute pseudomembranous candidiasis

A clinicopathologic study of forty-four cases
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      Abstract

      • 1.
        1. Clinical features are presented in forty-four cases of oral thrush with special reference to the natural course of the disease. Thrush may disappear spontaneously, and the onset of pain often may be related to shedding of the plaque.
      • 2.
        2. Oral thrush was found in about 10 per cent of severely debilitated patients, and it affected about one third of all dying patients in this series.
      • 3.
        3. The mouth may be the source or an early site of infection in widespread candidiasis.
      • 4.
        4. Histopathologic changes are described in fourteen cases, and the mechanism of shedding of the plaque is believed to be important in the healing of acute pseudomembranous candidiasis, as well as the pathogenesis of acute atrophic candidiasis.
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