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Research Article| Volume 21, ISSUE 5, P579-593, May 1966

Desquamative gingivitis and its response to topical triamcinolone therapy

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      Abstract

      A concept of desquamative gingivitis has been expressed. The condition probably is a reflection, clinically, of a variety of etiologic factors—both local and somatic in origin; in the majority of cases these influences cannot be elicited with clarity, and it is necessary to direct therapy to local alleviation of the gingival manifestations. The topical administration of triamcinolone acetate in Orabase constituted an effective form of therapy. The histopathologic characteristics of desquamative gingivitis include the detachment of epithelium, either intra- or subepithelially, with a variably severe connective tissue inflammatory reaction; it is difficult to collate this response to a specific etiologic agent.
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