Advertisement
Research Article| Volume 21, ISSUE 6, P764-769, June 1966

Download started.

Ok

Enzyme histochemistry of human oral carcinoma

      This paper is only available as a PDF. To read, Please Download here.

      Abstract

      Histochemical techniques for the determination of lactic dehydrogenase activity and succinic dehydrogenase activity were applied to the study of ten cases of epidermoid carcinoma of oral mucosa. A notable increase in lactic dehydrogenase activity was found, as well as a decrease in succinic dehydrogenase activity, when oral carcinoma was compared with normal oral mucosa.
      To read this article in full you will need to make a payment

      Purchase one-time access:

      Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
      One-time access price info
      • For academic or personal research use, select 'Academic and Personal'
      • For corporate R&D use, select 'Corporate R&D Professionals'

      References

        • Kabat E.A.
        • Furth J.
        A Histochemical Study of the Distribution of Alkaline Phosphatase in Various Normal and Neoplastic Tissues.
        Am. J. Path. 1941; 17: 303
        • Greenstein J.P.
        Esterase Activity of Normal and Neoplastic Tissues of the Mouse.
        J. Nat. Cancer Inst. 1944; 51: 31
        • Reiner L.R.
        • Rutenburg A.M.
        • Seligman A.M.
        Acid Phosphatase Activity in Human Neoplasms.
        Cancer. 1957; 10: 563
        • Monis B.
        • Rutenburg A.M.
        Alkaline Phosphatase Activity in Neoplastic and Inflammatory Tissues of Man.
        Cancer. 1960; 13: 538
        • Cohen R.B.
        • Nachlas M.M.
        • Seligman A.M.
        Histochemical Demonstration of Esterase in Malignant Tumors.
        Cancer Res. 1951; 11: 709
        • Lemon H.M.
        • Davison M.M.
        • Asimov I.
        Acid Phosphatase Activity of Normal and Neoplastic Human Tissues.
        Cancer. 1954; 7: 92
        • Monis B.
        • Weinberg T.
        Cytochemical Study of Esterase Activity of Human Neoplasms and Stromal Macrophages.
        Cancer. 1961; 14: 369
        • Gomori G.
        Distribution of Acid Phosphatase in the Tissues Under Normal and Under Pathological Conditions.
        Arch. Path. 1941; 32: 189
        • Santis H.
        • Shklar G.
        A Histochemical Study of Human Oral Carcinoma.
        Oral Surg., Oral Med. & Oral Path. 1964; 17: 84
        • Santis H.
        • Shklar G.
        • Chauncey H.H.
        Histochemistry of Experimentally Induced Leukoplakia and Carcinoma of the Hamster Buccal Pouch.
        Oral Surg., Oral Med. & Oral Path. 1964; 17: 207
        • Shklar G.
        Metabolic Characteristics of Experimental Hamster Pouch Carcinomas.
        Oral Surg., Oral Med. & Oral Path. 1965; 20: 336
        • Cataldo E.
        • Shklar G.
        • Chauncey H.H.
        Experimental Submaxillary Gland Tumors in Rats; Histology and Histochemistry.
        Arch. Path. 1964; 77: 305
        • Ogata T.
        • Mori M.
        Histochemical Study of Oxidative Enzymes in Vertebrate Muscle.
        J. Histochem. 1964; 12: 171
        • Morrison J.H.
        • Kronheim S.
        Cytochemical Demonstration of Succinie Dehydrogenase in Mouse Leukocytes.
        J. Histochem. 1962; 10: 402
        • Monis B.
        • Nachlas M.M.
        • Seligman A.M.
        Histochemical Study of Three Dehydrogenase Systems in Human Tumors.
        Cancer. 1959; 12: 1238
        • Warburg O.
        On the Origin of Cancer Cells.
        Science. 1956; 123: 309
        • Shklar G.
        Lactic Dehydrogenase Activity in Cytologic Smears of Normal Oral Mucosa and Epidermoid Carcinoma.
        Acta cytol. 1965; 9: 437