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Oral submucous fibrosis

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      Abstract

      On the basis of the literature and personal experience, we have discussed a pcculiar oral disease—submucous fibrosis—seen mainly among East Indians. The condition is chronic and is clinically characterized by blanching and stiffness of the oral mucosa. Histologically, the oral connective tissue becomes hyalinized and the overlying epithelium markedly atrophic. The disease may be due to an irritant (chili?), acting over a long period of time. Evidence is presented that submucous fibrosis may be considered an important precancerous condition in Southeast Asia.
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