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A case of Von Willebrand's disease has been presented. This familial disorder of great variability is characterized by prolonged bleeding time and a deficiency of a coagulation factor. A careful history is important in helping to determine the presence of a bleeding disorder. Repeated bleeding time determinations (Ivy method) and tourniquet tests are recommended for any patient whose history is suggestive of a bleeding disorder. An assay of Factor VIII is necessary before a diagnosis of Von Willebrand's disease can be made.
Surgical procedures can be carried out safely if fresh frozen plasma is given preoperatively and immediately postoperatively. Continued transfusions usually are not required.
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☆The opinions expressed herein are those of the authors and do not necessarily reflect the views of the Navy Department or the Naval Service at large.
© 1967 Published by Elsevier Inc.