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Abstract
The dental pulps of germ-free and conventional Sprague-Dawley rats were surgically
exposed and treated with corticosteroid and obtundent drugs and were either sealed
by means of a temporary cement or left exposed to the oral environment. The results
showed that, regardless of medication or closure, the pulps of conventional animals
degenerated, whereas the pulps of germ-free animals healed uneventfully as substantiated
by the formation of a reparative dentine bridge. The application of the steroid formula
immediately following pulpal exposure was neither helpful nor harmful.
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References
- Topical Use of Corticosteroids for the Relief of Pain Sensitivity of Dentine and Pulp.Oral Surg., Oral Med. & Oral Path. 1960; 13: 594-597
- Effects of Capping Compounds Containing Corticosteroids on the Human Dental Pulp.Helvet. odont. acta. 1962; 6: 23-32
- Effect of Triamcinolone With Tetracycline on the Dental Pulp and Apical Periodontium.J. Pros. Dent. 1965; 15: 144-152
- Experimental Pulpotomies in Rat Molars.J. D. Res. 1968; 37: 229-242
- Minimizing Pulpal Reactions With Prednisolone Therapy.J. Oral Therap. & Pharmacol. 1965; 2: 1-8
- Effects of Surgical Exposures of Dental Pulps in Germ-Free and Conventional Laboratory Rats.Oral Surg., Oral Med. & Oral Path. 1965; 20: 340-349
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© 1969 Published by Elsevier Inc.
