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Abstract
Changes in blood flow can be measured with the aid of infrared thermography and make
possible a comparative assessment of the vascular effect of vasoconstrictors and local
anesthetics. With Adrenalin, vasoconstriction sets in immediately following infiltration;
with POR-8,
∗Sandoz AG, Basel, Switzerland.
a sufficient vasoconstriction is observed only after 10 to 15 minutes. In both products,
ischemia subsides after 60 minutes. Adrenalin then reverses the reaction in reactive
hyperemia after 150 minutes, while the tissue infiltrated with POR-i returns to normal
after 120 minutes. When combining a local anesthetic with a vasoconstrictor, the intrinsic
vascular effect has to be considered. We experimentally proved that Novocain (procaine),
Hostacain (butanilicaine), and on a lower scale Xylocaine (lignocaine) have a vasodilator
effect. Citanest (prilocaine) demonstrates no vasodilatory effect. Carbocaine (mepivacaine)
produces a mild vasoconstriction.To read this article in full you will need to make a payment
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© 1979 Published by Elsevier Inc.
