Research Article| Volume 48, ISSUE 4, P324-336, October 1979

Ultrastructural characterization of intermediate cells of mucoepidermoid carcinoma of the parotid

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      Five cases of mucoepidermoid carcinoma of the parotid gland were studied ultrastructurally. In addition to epidermoid cells (tonofilament-rich) and mucous cells, three forms of intermediate cells were identified: mitochondria-rich cells, glycogen-rich cells, and ribosome-rich cells. Transitional forms of all cell types were observed. Ultrastructurally, cells rich in glycogen appeared to be the “clear cells” by light microscopy; cells rich in ribosomes appeared basophilic under light microscopy. Mitochondria-rich cells were lightly eosinophilic under light microscopy.
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        • Hübner G.
        • Kleinsasser O.
        Zur Feinstruktur und Genese des Mucoepidermoid Tumors der Speicheldrüsen.
        Virchows Arch. (Pathol. Anat.). 1970; 349: 281-296
        • Sugár J.
        • Tóth J.
        Die Ultrastruktur des Mukoepidermoidalen Karzinoms.
        Tbl. Allg. Pathol. Bd. 1967; 110: 329-334
        • Chen S.-Y.
        Mucoepidermoid Carcinoma of Minor Salivary Glands.
        Oral Surg. 1979; 47: 247-255
        • Tomita T.
        • Lotuaco L.
        • Talbott L.
        • Watanabe I.
        Mucoepidermoid Carcinoma of the Subglottis.
        Arch. Pathol. Lab. Med. 1977; 101: 145-148
        • Woodard B.H.
        • Shelburne J.D.
        • Vollmer R.T.
        • Postlethwait R.W.
        Mucoepidermoid Carcinoma of the Esophagus: A Case Report.
        Human Pathol. 1978; 9: 353-354
        • Sidhu G.S.
        • Waldo E.D.
        Oncocytic Change in Mucoepidermoid Carcinoma of the Parotid Gland.
        Arch. Pathol. 1975; 99: 663-666
        • Mohammed A.H.
        • Cherrick H.M.
        Glycogen-Rich Adenocarcinoma of Minor Salivary Glands.
        Cancer. 1975; 36: 1057-1066
        • Mohammed A.H.
        Ultrastructure of Glycogen-Rich Clear Cell Carcinoma of the Palate.
        J. Oral Pathol. 1976; 5: 103-121
        • Echevarria R.A.
        Ultrastructure of the Acinic Cell Carcinoma and Clear Cell Carcinoma of the Parotid Gland.
        Cancer. 1967; 20: 563-571
        • Johns M.E.
        • Regezi J.A.
        • Batsakis J.G.
        Oncocytic Neoplasms of Salivary Glands: An Ultrastructural Study.
        Laryngoscope. 1977; 87: 862-871
        • Sun C.N.
        • White H.J.
        • Thompson B.W.
        Warthin's Tumor of the Parotid Gland.
        Exp. Pathol. 1976; 12: 269-276
        • Eversole L.R.
        • Sabes W.R.
        Minor Salivary Gland Duct Changes Due to Obstruction.
        Arch. Otolaryngol. 1971; 94: 19-24
        • Bawer W.H.
        Old Age Changes in Human Parotid Glands With Special Reference to Peculiar Cells in Uncommon Salivary Gland Tumors.
        J. Dent. Res. 1950; 29: 686-687
        • Kay S.
        • Gerszten E.
        • Dennison S.M.
        Light and Electron Microscopic Study of a Rhabdomyoma Arising in the Floor of the Mouth.
        Cancer. 1969; 23: 708-716
        • Dardick I.
        Hibernoma: A Possible Model of Brown Fat Histogenesis.
        Human Pathol. 1978; 9: 321-329
        • D'Agostino A.N.
        • Ziter F.A.
        • Rallison M.L.
        • Bray P.F.
        Familial Myopathy With Abnormal Muscle Mitochondria.
        Arch. Neurol. 1968; 18: 388-401
        • Hulsmann N.C.
        • Bethlem J.
        • Meijer A.E.F.H.
        • Fleury P.
        • Schellens J.P.M.
        Myopathy With Abnormal Structure and Function of Muscle Mitochondria.
        J. Neurol. Neurosurg. Psychiatr. 1967; 30: 519-525
        • Luft R.
        • Ikhos D.
        • Palmieri G.
        • Ernster L.
        • Afzelius B.
        A Case of Severe Hypermetabolism of Nonthyroid Origin With a Defect in the Maintenance of Mitochondrial Respiratory Control: A Correlated Clinical, Biochemical and Morphological Study.
        J. Clin. Invest. 1962; 41: 1776-1804
        • Ghadially F.N.
        Ultrastructural Pathology of the Cell.
        in: Butterworths & Co., Ltd, London and Boston1975: 238-239
        • Eversole L.R.
        Histogenic Classification of Salivary Tumors.
        Arch. Pathol. 1971; 92: 433-443