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Research Article| Volume 59, ISSUE 2, P167-171, February 1985

Immunohistochemical identification of alpha-1-antitrypsin, alpha-1-antichymotrypsin, and lysozyme in focal hyperplastic gingivitis

  • Ruth Kivens
    Correspondence
    Reprint requests to: Dr. Ruth Kivens Department of Oral Pathology School of Dentistry University of Minnesota 515 Delaware St., S.E. Minneapolis, MN 55455
    Affiliations
    Department of Oral Pathology and Human Genetics, School of Dentistry, University of Minnesota Minneapolis, Minn. USA
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  • John J. Sauk
    Affiliations
    Department of Oral Pathology and Human Genetics, School of Dentistry, University of Minnesota Minneapolis, Minn. USA
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  • Robert A. Vickers
    Affiliations
    Department of Oral Pathology and Human Genetics, School of Dentistry, University of Minnesota Minneapolis, Minn. USA
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      Abstract

      Tissues from twenty-four patients with focal hyperplastic gingival lesions containing calcification were stained for lysozyme (muramidase), alpha-1-antitrypsin, and alpha-1-antichymotrypsin. In eighteen of the twenty-four cases the tissues stained positively for lysozyme, and in all instances the tissues stained positively for alpha-1-antitrypsin and alpha-1-antichymotrypsin. These data suggest that the fibrous components of these lesions are derived from tissue histiocytes.
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