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Research Article| Volume 59, ISSUE 5, P482-490, May 1985

Salivary epithelial-myoepithelial carcinomas of intercalated ducts: A clinical, electron microscopic, and immunocytochemical study

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      Abstract

      The salivary epithelial-myoepithelial carcinoma of intercalated duct origin is a distinctive, biologically low-grade carcinoma with a predilection for the parotid gland. Nine examples from the M.D. Anderson Hospital in Houston, Texas, bring the number of published cases to 33. Immunocytochemical (S-100 protein, myosin, and keratin) and electron-optic studies strongly support an active myoepithelial cell participation in the histogenesis of these carcinomas.
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      References

        • Batsakis JG
        Clear cell tumors of salivary glands.
        Ann Otol. 1980; 89: 196-197
        • Seifert G
        • Donath K
        Über das Vorkommen sog heller Zellen in Speicheldrusentumoren: Ultrastruktur und Differential-diagnose.
        Z Krebsforsch. 1978; 91: 165-182
        • Corio RL
        • Sciubba JJ
        • Brannon RB
        • Batsakis JG
        Epithelial-myoepithelial carcinoma of intercalated duct origin.
        Oral Surg Oral Med Oral Pathol. 1982; 53: 280-287
        • Hsu S-M
        • Raine L
        • Fanger H
        Use of avidin-biotin-peroxidase complex (ABC) in immunoperoxidase techniques: a comparison between ABC and unlabeled antibody (PAP) procedures.
        J Histochem Cytochem. 1981; 29: 577-580
        • Erlandson RA
        • Cardon-Cardo C
        • Higgins PJ
        Histogenesis of benign pleomorphic adenoma (mixed tumor) of the major salivary glands: an ultrastructural and immunohistochemical study.
        Am J Surg Pathol. 1984; 8: 803-820
        • Young JA
        • Van Lennep EW
        The morphology of salivary glands.
        in: Academic Press, Inc, London1978: 93-99
        • Saku T
        • Okabe H
        • Yagi Y
        • Sato E
        • Tsuda N
        A comparative study on the immunolocalization of keratin and myosin in salivary gland tumors.
        Acta Pathol Jpn. 1984; 34: 1031-1040
        • Hara K
        • Ito M
        • Takeuchi J
        • Iijima S
        • Endo T
        • Hidaka H
        Distribution of S-100 protein in normal salivary glands and salivary gland tumors.
        Virchows Arch Pathol (A). 1983; 401: 237-249
        • Kahn HJ
        • Marks A
        • Thom H
        • Baumal R
        Role of antibody to S-100 protein in diagnostic pathology.
        Am J Clin Pathol. 1983; 79: 341-347
        • Donner L
        • de Lanerolle P
        • Costa J
        Immunoreactivity of paraffin-embedded normal tissues and mesenchymal tumors for smooth muscle myosin.
        Am J Clin Pathol. 1983; 80: 677-681
        • de Lanerolle P
        • Stull JT
        Myosin phosphorylation during contraction and relaxation of tracheal smooth muscle.
        J Biol Chem. 1980; 255: 9993-10000
        • Regezi JA
        • Batsakis JG
        Histogenesis of salivary gland neoplasms.
        Otolaryngol Clin North Am. 1977; 10: 297-307
        • Batsakis JC
        Salivary gland neoplasia: an outcome of modified morphogenesis and cytodifferentiation.
        Oral Surg Oral Med Oral Pathol. 1980; 49: 229-232