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Review Article| Volume 59, ISSUE 6, P551-556, June 1985

Disseminated intravascular coagulation: A review

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      Abstract

      Disseminated intravascular coagulation (DIC) results from activation of the blood coagulation cascade by various disease processes. DIC may occur with blunt head trauma and, with severe head trauma, may reflect brain parenchymal injury. Oral and maxillofacial surgeons who treat traumatized patients should be aware of the implications of DIC with regard to patient management, diagnosis, and surgical considerations.
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      References

        • Clark J
        • Finelli R
        • Netsky M
        Disseminated intravascular coagulation following cranial trauma.
        J Neurosurg. 1980; 52: 266-268
        • Spero J
        • Lewis J
        • Hasiba V
        Disseminated intravascular coagulation findings in 346 patients.
        Thromb Haemost. 1980; 38: 33
        • Miner M
        • Kaufman M
        • Graham S
        • Maar F
        • Gildenberg P
        Disseminated intravascular coagulation fibrinolytic syndrome following head injury in children: frequency and prognostic implications.
        J Pediatr. 1982; 100: 687-691
      1. DM. 1977; 23: 43-51
        • Feinstein D
        Diagnosis and management of disseminated intravascular coagulation: the role of heparin therapy.
        Blood. 1982; 60: 284-287
        • Drayer B
        • Poser C
        Disseminated intravascular coagulation and head trauma.
        JAMA. 1975; 231: 174-175
        • Colman R
        • Robboy S
        • Minna J
        Disseminated intravascular coagulation: an approach.
        Am J Med. 1972; 52: 679-699
        • Deykin D
        Clinical challenge of disseminated intravascular coagulation.
        N Engl J Med. 1970; 283: 636-644
        • Innes D
        • Sevitt S
        Coagulation and fibrinolysis in injured patients.
        J Clin Pathol. 1964; 17: 1-13
        • Saltzman EW
        Does intravascular coagulation occur in hemorrhagic shock in man?.
        J. Trauma. 1968; 8: 867-870
        • Goodnight S
        • et al.
        Difribrination after brain tissue destruction.
        N Engl J Med. 1974; 290: 1043-1047
        • Van Der Sande S
        • et al.
        Head injury and coagulation disorders.
        J Neurosurg. 1978; 49: 357-365
        • Hamilton J
        • Stalker A
        • Douglas A
        Disseminated intravascular coagulation: a review.
        J Clin Pathol. 1978; 31: 609-619
        • Vecht CH
        • Sibinga C
        • Mindermound J
        Disseminated intravascular coagulation and head injury.
        J Neurol. 1975; 38: 567-571
        • Lim R
        • Olcott C
        • Robinson A
        • Blaisdell F
        Platelet Response and Coagulation Changes Following Massive Blood Replacement.
        J Trauma. 1973; 13: 577-580
        • Shimamuria K
        • et al.
        Distribution patterns of microthrombi in disseminated intravascular coagulation.
        Arch Pathol Lab Med. 1983; 107: 543-547
        • Schwartzman R
        • Hill J
        Neurologic complications of disseminated intravascular coagulation.
        Neurology. 1982; 32: 791-796
        • String T
        • Robinson A
        • Blasdell F
        Massive trauma: effect on intravascular coagulation on prognosis.
        Arch Surg. 1971; 102: 406-410
        • Rodriquez-Erdman F
        Bleeding due to increased intravascular clotting.
        N Engl J Med. 1965; 273: 1370-1378
        • Bowie M
        • Owen C
        Hemostatic failure in clinical medicine.
        Semin Hematol. 1977; 14: 341-364
        • Merskey G
        • Johnson A
        • Kleiner G
        • Wohl M
        Defibrination syndrome: Clinical features and laboratory diagnosis.
        Br J Haematol. 1967; 13: 528-548
        • Silver D
        Coagulopathies and surgeons.
        J Surg Res. 1974; 16: 429-439
        • Nossel HH
        Radioimmunoassay of fibrinopeptides in relation to intravascular coagulation and thrombosis.
        N Engl J Med. 1976; 295: 428
        • Cafferata M
        • Aggeler P
        • Robinson A
        • Blaisdell F
        Intravascular coagulation in the surgical patient.
        Am J Surg. 1969; 118: 281-288
        • Hardaway RM
        Syndromes of disseminated intravascular coagulation with special reference to shock and hemorrhage.
        Charles C Thomas, Publisher, Springfield, Ill1966
        • Preston F
        • Malia R
        • Sworn
        • et al.
        Disseminated intravascular coagulation as a consequence of cerebral damage.
        J Neurol Neurosurg Psychiatry. 1974; 37: 241-248
        • Toui D
        Fibrinolytic activity of human brain: a histochemic study.
        Acta Neurol Scand. 1973; 49: 152
        • Strinchini A
        • et al.
        Defibrination and head injury (letter).
        Lancet. 1974; 2: 957
        • Murakami W
        • Davidson T
        • Marshall L
        Fatal epistaxis in craniofacial trauma.
        J Trauma. 1983; 23: 57-61
        • Keimowitz RM
        • Annis BL
        Disseminated intravascular coagulation associated with massive brain injury.
        J Neurosurg. 1973; 39: 178
        • Druskin M
        • Drisanski R
        Afibrinogenemia with severe head trauma (letter).
        JAMA. 1972; 219: 755-756
        • Dalens B
        • Bezon M
        Coagulopathy following brain injury (letter).
        J Pediatr. 1983; 102: 166
        • Vecht C
        • Sibinga C
        Head injury and defibrination.
        Lancet. 1974; 2: 905
        • Sharp AA
        Diagnosis and management of disseminated intravascular coagulation.
        Br Med Bull. 1977; 33: 265-272
        • Robboy S
        • Mihm M
        • Colman R
        • Minna J
        The skin in disseminated intravascular coagulation.
        Br J Dermatol. 1973; 58: 221-229
        • Kowaiski E
        • Kopec M
        • Niewlarowski S
        An evaluation of the euglobulin method for the demonstration of fibrinolysis.
        J Clin Pathol. 1959; 12: 215
        • Robboy S
        • Colman R
        • Minna J
        Pathology of disseminated intravascular coagulation.
        Hum Pathol. 1972; 3: 327-343
        • Kaufman M
        • Moak J
        • Olson J
        • Miner M
        • Ducket R
        • Pruessner J
        • Gildenberg P
        Delayed and recurrent intracranial hematoma related to disseminated intravascular clotting and fibrinolysis in head injury.
        Neurosurgery. 1980; 7: 495
        • Lerner R
        • Rappaport S
        • Siemsen J
        • Spitzer S
        Disappearance of fibrinogen I after endotoxin; effects of a first and second injection.
        Am J Physiol. 1968; 214: 532-537
        • Counts R
        • Haisch C
        • Simon T
        • Maxwell N
        • Heimbach D
        • Carrico C
        Hemostasis in massively transfused trauma patients.
        Ann Surg. 1979; 190: 91-99
        • Bick R
        • Dukes M
        • Wilson W
        • Fekete L
        Antithrombin III as a diagnostic and in disseminated intravascular coagulation.
        Thromb Res. 1977; 10: 721-728
        • Wintrobe M
        • Lee G
        • Boggs D
        • Bithell C
        • Foerster J
        • Athens J
        • Lukens J
        Acquired coagulation disorders.
        in: Clinical Hematology. ed. 8. Lea & Febiger, Philadelphia1981: 1213
        • Colman R
        • Robboy S
        • Minna S
        Disseminated intravascular coagulation: a reappraisal.
        Ann Rev Med. 1979; 30: 359
        • Corrigan JJ
        Disseminated intravascular coagulopathy.
        Pediatr Rev. 1979; 1: 37
        • Green D
        • Seeler R
        • Allen N
        • et al.
        The role of heparin in the management of consumption coagulopathy.
        Med Clin North Am. 1972; 56: 193-198
        • Cash JD
        Disseminated intravascular coagulation.
        in: Poller L Recent advances in blood coagulation. ed. 2. Churchill Livingston, Edinburgh1977: 293-311
        • Seaman AJ
        The recognition of intravascular clotting: the plasma protamine paracoagulation test.
        Arch Intern Med. 1970; 125: 1016-1026
        • Gralnick HR
        • Greipp P
        Thrombosis with epsilon aminocaproic acid therapy.
        Am J Clin Pathol. 1971; 56: 151-154
        • Cooper M
        • Bowie E
        • Ocoen C
        Evaluation of patients with fibrin split products in their serum.
        in: ed. 2. May Clin Proc. 49. 1974: 654-657
        • Kim H
        • Suzuki M
        • Lie S
        • Titis J
        Clinically unsuspected disseminated intravascular coagulation: an autopsy survey.
        Am J Clin Pathol. 1976; 66: 31
      2. Sherry S: Mechanisms of fibrinolysis. In Williams W, Beutler E, Erslev A (editors): Hematology, New York, McGraw-Hill Book Company.

        • Versasian R
        • Rosner T
        • Gilmore W
        Postsurgical hemorrhage resulting from a drug-induced circulating anticoagulant: report of case.
        J Oral Maxillofac Surg. 1980; 38: 688-690