This paper is only available as a PDF. To read, Please Download here.
Abstract
The maxillary molar pulps of germ-free rats were mechanically exposed, and suspensions
of a strain of freshly grown Streptococcus mutans were applied to the pulp wounds. The pulps were left open to the oral environment,
and the animals were maintained in the isolator until they were killed in groups after
2, 7, and 28 days. After 2 days there was little evidence of any pulp response. In
the 7-day group early pulp necrosis was present. No evidence of inflammatory infiltration
was delected in either the 2- or 7-day animals. After 28 days there was extensive
pulp necrosis in many specimens. Dentine bridges were present in fewer than one fourth
of the teeth.
To read this article in full you will need to make a payment
Purchase one-time access:
Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online accessOne-time access price info
- For academic or personal research use, select 'Academic and Personal'
- For corporate R&D use, select 'Corporate R&D Professionals'
Subscribe:
Subscribe to Oral Surgery, Oral Medicine, Oral Pathology and Oral RadiologyAlready a print subscriber? Claim online access
Already an online subscriber? Sign in
Register: Create an account
Institutional Access: Sign in to ScienceDirect
References
- The effects of surgical exposures of dental pulps in germ-free and conventional laboratory rats.Oral Surg Oral Med Oral Pathol. 1965; 20: 340-349
- Bacterial contamination and the exposed pulp.Br Dent J. 1976; 140: 231-236
- Bacterial contamination and the toxicity of silicate and zinc phosphate cement.Br Dent J. 1979; 146: 7-13
- Pulpal reaction to polycarboxylate and zinc phosphate cements used with inlays in deep cavities.J Am Dent Assoc. 1977; 94: 308-310
- The relationship of bacterial penetration and pulpal pathosis in carious teeth.Oral Surg Oral Med Oral Pathol. 1966; 22: 59-65
- Discussion of vascular permeability and other factors in the modulation of the inflammatory response.J Endod. 1977; 3: 214-217
- Bacterial contamination as a factor in the healing of pulp exposures.Oral Surg Oral Med Oral Pathol. 1974; 38: 441-450
- Pulpal and periapical tissue responses in conventional and monoinfected gnotobiotic rats.Oral Surg Oral Med Oral Pathol. 1974; 37: 783-802
- Pulp response to dental caries induced by Streptococcus mutans.Oral Surg Oral Med Oral Pathol. 1982; 53: 88-92
- A simplified fibreglass germ-free isolator with facilities for performing dental surgery on rats.Lab Anim. 1970; 4: 233-238
- Dental caries and alveolar bone loss in gnotobiotic rats infected with capsule forming streptococci of human origin.Arch Oral Biol. 1966; 11: 549-560
- An investigation into the histological changes produced in the rat molar pulp in response to caries and various micro-organisms.in: M.D.S. Thesis. University of London, London1978
- Periapical destructions caused by experimental pulpal inoculation of Streptococcus mutans in rats.Oral Surg Oral Med Oral Pathol. 1975; 39: 479-487
- Migration of materials and microorganisms in the dental pulp of dogs and rats.J Endodont. 1982; 8: 53-58
- The effect of three proprietary lining materials on micro-organisms in carious dentine.Br Dent J. 1977; 143: 231-235
Article info
Footnotes
☆The experimental work described in this article formed part of the M.D.S. thesis submitted by Prof. Paterson to the University of London.
Identification
Copyright
© 1987 Published by Elsevier Inc.
