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Research Article| Volume 64, ISSUE 2, P264-267, August 1987

Oral complications of high-dose melphalan in multiple myeloma

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      Abstract

      Four patients with multiple myeloma refractory to conventional chemotherapy received high-dose melphalan. All experienced multiple oral complications. Extensive neutropenic ulceration and orofacial herpes simplex virus infection caused considerable morbidity in three patients during prolonged periods of neutropenia.
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