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Research Article| Volume 64, ISSUE 1, P30-34, July 1987

Systemic lupus erythematosus: A consideration for antimicrobial prophylaxis

  • Author Footnotes
    * Chief General Practice Resident, Department of General Practice.
    Monte K. Zysset
    Footnotes
    * Chief General Practice Resident, Department of General Practice.
    Affiliations
    The University of Texas Health Science Center at San Antono San Antonio, Texas, USA
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  • Author Footnotes
    ** Assistant Professor, Department of General Practice.
    Michael T. Montgomery
    Correspondence
    Reprint requests to: Dr. Michael T. Montgomery Department of General Practice School of Dentistry The University of Texas Health Science Center 7703 Floyd Curl Dr. San Antonio, TX 78284-7914
    Footnotes
    ** Assistant Professor, Department of General Practice.
    Affiliations
    The University of Texas Health Science Center at San Antono San Antonio, Texas, USA
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  • Author Footnotes
    *** Associate Professor, Department of Community Dentistry.
    Spencer W. Redding
    Footnotes
    *** Associate Professor, Department of Community Dentistry.
    Affiliations
    The University of Texas Health Science Center at San Antono San Antonio, Texas, USA
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  • Author Footnotes
    **** Assistant Professor, Department of Medicine.
    Louis J. Dell'Italia
    Footnotes
    **** Assistant Professor, Department of Medicine.
    Affiliations
    The University of Texas Health Science Center at San Antono San Antonio, Texas, USA
    Search for articles by this author
  • Author Footnotes
    * Chief General Practice Resident, Department of General Practice.
    ** Assistant Professor, Department of General Practice.
    *** Associate Professor, Department of Community Dentistry.
    **** Assistant Professor, Department of Medicine.
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      Abstract

      Endothelial damage to heart valves, similar to that seen with rheumatic heart disease, occurs in 50% of all patients with systemic lupus erythematosus. Bacterial endocarditis is a consequence in 1% to 4% of these patients. This rate is greater than the incidence of endocarditis after rheumatic heart disease and compares favorably with the incidence of endocarditis in patients with prosthetic heart valves. At present, it is not possible to accurately delineate the subpopulation of patients with SLE that is at risk for this disease; hence, it is recommended that antibiotic prophylaxis (standard regimen suggested by the American Heart Association) be considered for all patients with systemic lupus erythematosus undergoing dental procedures associated with transient bacteremias.
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