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Abstract
Three materials, which had been previously found to be toxic when applied as pulp-capping
agents in conventional rat molar pulps, were retested in germ-free rats. All produced
much more favorable responses in the pulp, with a lack of inflammation and the presence
of dentine bridges in the majority of teeth. It appears that much of the pulp damage
previously attributed to the chemical toxicity of materials may be caused by the presence
of bacteria. The design of studies intended to evaluate the response of the pulp to
materials should include staining techniques that will detect the presence of bacteria
on the floors of test cavities.
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References
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Article info
Footnotes
☆Part of the material contained in this paper was included in the Ph.D. theses submitted to the University of London by Dr. Watts and Professor Paterson.
Identification
Copyright
© 1987 Published by Elsevier Inc.
