Research Article| Volume 64, ISSUE 4, P475-479, October 1987

Tissue response to retrograde root fillings in the ferret canine: A comparison of a glass ionomer cement and gutta-percha with sealer

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      Tissue healing was compared after apicectomy and filling of ferret lower canines with glass ionomer (Ketacfil) or gutta-percha/sealer (Tubliseal). Both materials provoked an inflammatory response after 7 days, but the response to glass ionomer was less severe. The response after 28 days was different. Mild inflammation related to the gutta-percha was still present, but no inflammation was found in relation to the glass ionomer. Bone infill was quite advanced in all specimens at 28 days but was more complete in the glass ionomer specimens, with intimate contact between the bone and cement.
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        • Phillips WH
        • Maxmen HA
        A practical root resection technique for young permanent anterior teeth.
        Dent Digest. 1941; 47: 60-64
        • Kopp WK
        • Kresberg H
        Apicectomy with retrograde gold foil—a new technique.
        NY State Dent J. 1973; 39: 8-11
        • Oynick J
        • Oynick T
        A study of a new material for retrograde fillings.
        J Endod. 1978; 4: 203-206
        • Persson G
        • Lennartson B
        • Lundström I
        Results of retrograde root filling with special reference to amalgam and Cavit as root-filling materials.
        Sven Tandlak Tidskr. 1974; 67: 123-313
        • Delivanis P
        • Tabibi A
        Comparative sealability study of different retrofilling materials.
        Oral Surg Oral Med Oral Pathol. 1978; 45: 273-281
        • Dalal MB
        • Gohil KS
        Comparison of silver amalgam, glass ionomer cement, and gutta percha as retrofilling materials; an in vivo and an in vitro study.
        J Indian Dent Assoc. 1983; 55: 153-158
        • Abdal AK
        • Retief DH
        • Jamison HC
        The apical seal via the retrosurgical approach, 2. An evaluation of retrofilling materials.
        Oral Surg Oral Med Oral Pathol. 1982; 54: 213-218
        • Wilson AD
        • Kent BE
        A new translucent cement for dentistry—the glass ionomer cement.
        Br Dent J. 1972; 132: 133-135
        • Tobias RS
        • Browne RM
        • Plant CG
        • Ingram DW
        Pulpal response to a glass ionomer cement.
        Br Dent J. 1978; 144: 345-350
        • Kawahara H
        • Imanishi Y
        • Oshima H
        Biological evaluation on glass ionomer cement.
        J Dent Res. 1979; 58: 1080-1086
        • Prosser HJ
        • Powis DR
        • Brant P
        • Wilson AD
        Characterization of glass-ionomer cements, 7. The physical properties of current materials.
        J Dent. 1984; 12: 231-240
        • Zmener O
        • Cabrini RL
        Adhesion of human blood monocytes and lymphocytes to different endodontic cements: a methodological in vitro study.
        J Endod. 1986; 12: 150-155
        • Holland GR
        Periapical response to apical plugs of dentine and calcium hydroxide in ferret canines.
        J Endod. 1984; 10: 71-74
        • Marcotte LR
        • Dowson J
        • Rowe NH
        Apical healing with retrofilling materials amalgam and gutta percha.
        J Endod. 1975; 1: 63-65
        • Hotta Y
        An experimental study on regeneration of cementum, periodontal ligament and alveolar bone in the intradentinal cavities of the root canal filled teeth in dogs [English abstract].
        J Tokyo Dent Coll Soc. 1977; 77: 487-498
        • Corcoran JF
        • Sieraski SM
        • Ellison RL
        Osseous healing kinetics after apicoectomy in monkeys: a quantitative histological appraisal.
        J Endod. 1985; 11: 269-274