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Abstract
Peripheral (extraosseous or soft tissue) odontogenic tumors are rare lesions that
occur in the soft tissue overlying the tooth-bearing areas of the mandible and the
maxilla. A review of the English-language literature revealed only 48 well-documented
cases of peripheral epithelial odontogenic tumors. Thirty-two were peripheral ameloblastomas;
six were peripheral adenomatoid odontogenic tumors; nine were peripheral calcifying
epithelial odontogenic tumors; and one was a peripheral squamous odontogenic tumor.
An additional four cases were reported as peripheral ameloblastomas in extragingival
locations, but their odontogenic origin is debatable. Although the peripheral ameloblastoma
is histologically similar to its central counterpart, it differs in its clinical features
and biologic behavior. It does not exhibit an aggressive, destructive behavior and
does not invade the underlying bone. Conservative excision of the tumor with minimal
but adequate margins is the treatment of choice and recurrences are uncommon. This
benign biologic behavior appears to be true also for lesions diagnosed as peripheral
calcifying epithelial odontogenic tumors and undoubtedly is true for the peripheral
adenomatoid odontogenic tumors.
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© 1987 Published by Elsevier Inc.