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Abstract
The relationship between oral discomfort and menopause was assessed in 149 women who
were divided into three groups determined by response to a questionnaire. The groups
consisted of 50 premenopausal women (30 to 43 years old), 47 menopausal women not
receiving medical treatment for symptoms of menopause (37 to 66 years old), and 52
menopausal women attending a menopause clinic before and during treatment for menopausal
symptoms (30 to 63 years old). The last group had a general medical assessment, including
psychological and oral examinations with oral smears and cultures, and the following
blood tests: full blood examination, follicle-stimulating hormone, oestradiol, folate,
vitamin B12, iron, and total iron binding capacity. Of this last group, 33% reported oral discomfort
but had no obvious organic abnormalities that could account for this symptom. The
prevalence of oral discomfort was found to be significantly higher in perimenopausal
and postmenopausal women (43%) than in premenopausal women (6%). The results also
showed an association between oral discomfort and psychological symptoms in menopausal
women. Approximately two thirds of the menopausal women with oral discomfort, but
without oral clinical signs, found that this symptom was relieved after hormone replacement
therapy. The results indicated that oral discomfort is a common symptom of menopause,
that it often occurs without overt clinical signs, and that it frequently resolves
during appropriate hormone replacement therapy.
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© 1989 Published by Elsevier Inc.
