Abstract
Objective: A questionnaire was used to investigate the prevalence of self-assessed sensations
of painful mouth (PM) and dry mouth (DM) in menopause-aged women. Special attention
was paid to the association of the use of hormone replacement therapy (HRT) with oral
symptoms. Our hypothesis was that women using HRT have fewer oral symptoms than those
who do not use HRT. Study Design: Patients were selected from among 50- to 58-year-old women attending a communal mammography
screening program in Helsinki, Finland. Every fifth woman was offered a structured
questionnaire. Results: Completed questionnaires were received from 3173 women (response rate, 65%). Of the
total sample, 46.8% (n = 1486) used HRT. The occurrence of PM was 8.2% (n = 259) and
DM, 19.9% (n = 631). Climacteric symptoms were reported by 24% (n = 761) of the total
sample and by 19.2% (n = 285) of the HRT users. According to logistic regression analyses,
climacteric symptoms were found to be predictive of PM (P =.000) and DM (P =.000). The use of HRT also increased the occurrence of PM (P =.03). However, as a single covariate in our statistical model, the use of HRT was
not a predictor of PM. The use of HRT also did not correlate with the occurrence of
DM. Conclusions: The occurrence of PM and of DM seemed to be associated with climacteric symptoms
in general, and the use of HRT did not prevent the oral symptoms studied. (Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2001;92:276-80)
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References
- Prospective study of aetiological factors in burning mouth syndrome.Br Med J. 1988; 296: 1243-1246
- General health factors and denture function in patients with burning mouth syndrome and matched control subjects.J Oral Rehabil. 1995; 22: 887-895
- Salivary flow rate, buffering capacity and yeast counts in 187 consecutive adult patients from Kuopio, Finland.Scand J Dent Res. 1994; 102: 227-234
- Patients with burning mouths. A clinical investigation of causative factors, including the climacteric and diabetes.Br Dent J. 1978; 145: 9-16
- Burning mouth syndrome: prevalence and associated factors.J Oral Pathol Med. 1999; 28: 350-354
- Oral discomfort at menopause.Oral Surg Oral Med Oral Pathol. 1989; 67: 535-540
- Reported burning mouth symptoms among middle-aged and elderly women.Eur J Oral Sci. 1997; 105: 539-543
- Prevalence of oral and facial pain and discomfort: preliminary results of a mail survey.Community Dent Oral Epidemiol. 1987; 15: 169-172
- Estimated prevalence and distribution of reported orofacial pain in the United States.J Am Dent Assoc. 1993; 124: 115-121
- Burning mouth in a Finnish adult population.Community Dent Oral Epidemiol. 1993; 21: 67-71
- Burning mouth syndrome. Evaluation of multiple variables among 85 patients.Oral Surg Oral Med Oral Pathol. 1993; 75: 303-307
- Efficacy of hormone replacement therapy in postmenopausal women with oral discomfort.Oral Surg Oral Med Oral Pathol. 1992; 73: 570-574
- An assessment of salivary function in healthy premenopausal and postmenopausal females.J Gerontol. 1991; 46: M11-M15
- Oestrogens and psychological well-being.Ann Med. 1997; 29: 283-290
- LIMDEP 6.0.Econometric Software Inc, Belport, NY1992
- Oral manifestations during the female climacteric (the postmenopausal syndrome).Oral Surg Oral Med Oral Pathol. 1951; 4: 1234-1243
- Use of hormone replacement therapy in 1976-89 by 45-64-year-old Finnish women.J Epidemiol Community Health. 1991; 45: 277-280
- Why do postmenopausal women discontinue hormone replacement therapy?.Maturitas. 1999; 33: 99-105
- Burning mouth syndrome: a review of 98 cases.J Oral Med. 1987; 42: 7-9
- Glossodynia: A study of idiopathic orolingual pain.J Am Dent Assoc. 1946; 33: 1422-1432
- Clinical features of burning mouth syndrome.Oral Surg Oral Med Oral Pathol. 1987; 63: 30-36
Article info
Publication history
Accepted:
May 16,
2001
Received in revised form:
April 18,
2001
Received:
February 28,
2001
Footnotes
*Supported by grants from the Research Foundation (EVO) of the Helsinki University Central Hospital, The Finnish Dental Association, and Orion Pharmaceuticals, Espoo, Finland.
**Reprint requests: Laura Tarkkila, DDS, MSc, Institute of Dentistry, PO Box 41, FIN–00014 University of Helsinki, Finland, [email protected]
Identification
Copyright
© 2001 Mosby, Inc. Published by Elsevier Inc. All rights reserved.
