Abstract
Objective. The objective was to study the clinicopathologic features of rhabdomyosarcoma (RMS)
of the oral and maxillofacial region in Jordanians. Study Design. Data were collected from records of patients treated between 1989 and 2000 at the
Maxillofacial Unit of Jordan University of Science and Technology. The main outcome
measures were age, gender, location, stage of disease, histopathologic type, treatment
received, follow-up period, and eventual outcome. Results. Nine patients with RMS aged 4 to 17 years were found, with a male to female ratio
of 2:1. Six (67%) bony sites and 7 (78%) soft tissue sites were involved. The extent
of disease was locoregional in 8 (89%) cases, nodal in 3 (33%) cases, and distant
metastatic in 2 (22%) cases. The Intergroup Rhabdomyosarcoma Study classification
of clinical groups was as follows: 2 (22%) cases in stage II, 5 (56%) cases in stage
III, and 2 (22%) cases in stage IV. The histopathologic types found were 6 (67%) embryonal,
2 (22%) alveolar, and 1 (11%) undifferentiated. Triple agent chemotherapy was used
in the treatment of 8 cases, singly or in combination with surgery or radiotherapy.
Two patients are still alive, and 5 patients have died of disease. Conclusions. The clinicopathologic features of maxillofacial RMS in this group of Jordanians are
different from those of people from other countries. Further studies are needed to
have a better understanding of the behavior of RMS in the oral and maxillofacial area.
(Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2002;93:580-5)
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Article info
Publication history
Accepted:
January 24,
2002
Received in revised form:
September 14,
2001
Received:
August 9,
2001
Footnotes
*Reprint requests: Taiseer Al-Khateeb MScD Department of Oral & Maxillofacial Surgery Faculty of Dentistry Jordan University of Science & Technology PO Box 3030 Irbid Jordan [email protected]
Identification
Copyright
© 2002 Mosby, Inc. Published by Elsevier Inc. All rights reserved.
