Abstract
Objective. The purpose of this study was to compare the efficacy of 2 different concentrations
of ropivacaine with lidocaine containing epinephrine for intraligamentary anesthesia.
Study Design. Ethical approval was obtained and a randomized, double-blind, cross-over volunteer
investigation was conducted. Twenty-four volunteers had intraligamentary injections
of 2% lidocaine with 1:80,000 epinephrine, 0.75% ropivacaine, or 1% ropivacaine at
the upper lateral incisor and lower first bicuspid teeth. The response of the test
teeth to electrical pulp testing and the reaction of the gingiva to sharp probing
were assessed up to 29 minutes after injection. Injection discomfort and side effects
were also recorded. Data were analyzed by using the chi-square test and analysis of
variance. Results. Lidocaine with epinephrine was more successful than the ropivacaine solutions in
obtaining pulpal anesthesia (chi-square = 12; P <.002) and produced longer-lasting pulpal (F = 21; P <.001) and soft tissue (F = 16; P <.001) anesthesia. Injection discomfort and incidence of side effects were similar
between solutions, and none produced serious adverse effects. Conclusion. Lidocaine with epinephrine is more effective than ropivacaine as an intraligamentary
anesthetic. (Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2002;93:469-73)
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Article info
Publication history
Accepted:
October 15,
2001
Received in revised form:
September 3,
2001
Received:
June 6,
2001
Footnotes
*Reprint requests:J. G. Meechan, BSc, BDS, FDSRCPS, PhD, Oral and Maxillofacial Surgery, Dental School, University of Newcastle upon Tyne, Framlington Place, Newcastle upon Tyne, England, NE2 4BW, United Kingdom, [email protected]
**Supported by a grant from AstraZeneca.
*Senior Lecturer and Honorary Consultant, Department of Oral and Maxillofacial Surgery.
Identification
Copyright
© 2002 Mosby, Inc. Published by Elsevier Inc. All rights reserved.
