Advertisement
Oral Medicine| Volume 93, ISSUE 4, P435-439, April 2002

Nasal cocaine abuse and centrofacial destructive process: Report of three cases including treatment

      Abstract

      We report 3 new cases of a centrofacial destructive process associated with chronic nasal abuse of cocaine. This complex first described in 1988 is a rare entity involving sinonasal tract necrosis after cocaine abuse. Of special interest in this report is a male patient with columella and lip involvement instead of the more usual rhinopalatal destruction. This cocaine abuse complex should be included in the differential diagnosis of centrofacial midline destructive processes in young patients as the first diagnostic possibility. We suggest a management strategy for these patients. (Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2002;93:435-9)
      To read this article in full you will need to make a payment

      Purchase one-time access:

      Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
      One-time access price info
      • For academic or personal research use, select 'Academic and Personal'
      • For corporate R&D use, select 'Corporate R&D Professionals'

      References

        • Cregler LL
        • Mark H
        Medical complications of cocaine abuse.
        N Engl J Med. 1986; 315: 1495-1500
        • Schwarz RH
        • Estroff T
        • Fairbanks DNF
        • Hoffman NG
        Nasal symptoms associated with cocaine abuse during adolescence.
        Arch Otolaryngol Head Neck Surg. 1989; 115: 63-64
        • Deutsch HI
        • Millard Jr, DR
        A new cocaine abuse complex: involvement of nose septum, palate and pharynx.
        Arch Otolaryngol Head Neck Surg. 1989; 115: 235-237
        • Daggett RB
        • Haghighi P
        • Terkeltaub RA
        Nasal cocaine abuse causing an aggressive midline intranasal and pharyngeal destructive process mimicking midline reticulosis and limited Wegener granulomatosis.
        J Rheumatol. 1990; 17: 838-840
        • Becker GD
        • Hill S
        Midline granuloma due to illicit cocaine use.
        Arch Otolaryngol Head Neck Surg. 1988; 114: 90-91
        • Lancaster J
        • Belloso A
        • Wilson A
        • Path MRC
        • McCormick M
        Rare case of naso-oral fistula with extensive osteocartilaginous necrosis secondary to cocaine abuse: review of otorhinolaryngological presentations in cocaine addicts.
        J Laryngol Otol. 2000; 114: 630-633
        • Kurloff DB
        • Kimmelman CP
        Osteocartilaginous necrosis of the sinonasal tract following cocaine abuse.
        Laryngoscope. 1989; 99: 918-924
        • Sittel C
        • Eckel HE
        Nasal cocaine abuse presenting as a central facial destructive granuloma.
        Eur Arch Otorhinolaryngol. 1998; 255: 446-447
        • Caravaca A
        • Casas F
        • Mochón A
        • De Luna A
        • San Martín A
        • Ruiz A
        Necrosis centrofacial secundaria a abuso de cocaína.
        Acta Otorrinolaringol Esp. 1999; 505: 414-416
        • Mc Donald TJ
        • De Reimee RA
        • Kern EB
        • Harrison Jr, EG
        Nasal manifestations of Wegener's granulomatosis.
        Laryngoscope. 1974; 84: 2101-2112
        • Gaulard P
        • Henni T
        • Marolleau JP
        • Haioun C
        • Henni Z
        • Voisin MC
        • et al.
        Lethal midline granuloma (polymorphic reticulosis) and lymphomatous granulomatosis: evidence for a monoclonal T-cell lymphoma proliferative disorder.
        Cancer. 1988; 62: 705-710
        • Tsokos M
        • Fauci AS
        • Costa J
        Idiopathic midline destructive disease (IMDD): a subgroup of patients with the “midline granuloma” syndrome.
        Am J Clin Pathol. 1982; 77: 162-168