Mucosal leishmaniasis is a chronic infection that affects the upper respiratory tract
and/or the oral mucosa caused by Leishmania protozoan parasites. We present two cases of oral leishmaniasis and discuss the different
diagnostic strategies and treatment. In both cases, the patients were male, 60 and
94 years of age, and presented with lesions on the soft palate. In the first patient,
the final diagnosis was made on the basis of histopathologic examination. In the second
case, polymerase chain reaction and Montenegro skin test were necessary to confirm
the diagnosis. The first patient was treated with meglumine antimoniate (Glucantime),
and the lesions healed after 2 months. In the second case, the patient received treatment
with liposomal amphotericin B but later died as a result of generalized infection.
Mucosal leishmaniasis is a highly disfiguring disease. Early diagnosis is important
to prevent a lethal outcome.
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Article info
Publication history
Published online: March 09, 2016
Accepted:
February 23,
2016
Received in revised form:
February 16,
2016
Received:
July 19,
2015
Identification
Copyright
© 2016 Elsevier Inc. All rights reserved.
