The aim of this study was to investigate the connection between preradiotherapy dental extractions and self-reported health-related QoL.
Retrospective data on patients treated with radiotherapy for oropharyngeal cancer were pooled with the results of a cross-sectional survey.
Greater than eight preradiotherapy dental extractions, p16 negative status, female gender, and positive smoking status were associated with statistically significant reduced QoL.
Preradiotherapy dental extractions do not result in improved QoL and, in fact, may worsen it.
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- Osteoradionecrosis of the mandible: scientific basis for clinical staging.Am J Clin Oncol. 2002; 25: 168-171
- Osteoradionecrosis of the jaws: a retrospective study of the background factors and treatment in 104 cases.J Oral Maxillofac Surg. 1997; 55 (discussion 545-546): 540-544
- Evidence supporting pre-radiation elimination of oral foci of infection in head and neck cancer patients to prevent oral sequelae. A systematic review.Oral Oncol. 2015; 51: 212-220
- Oral health status of 207 head and neck cancer patients before, during and after radiotherapy.Clin Oral Investig. 2008; 12: 19-24
- Efficacy of routine pre-radiation dental screening and dental follow-up in head and neck oncology patients on intermediate and late radiation effects. A retrospective evaluation.Radiother Oncol. 2011; 101: 403-409
- Do pre-irradiation dental extractions reduce the risk of osteoradionecrosis of the mandible?.Head Neck. 2007; 29: 528-536
- Oral symptoms and functional outcome related to oral and oropharyngeal cancer.Support Care Cancer. 2011; 19: 1327-1333
- A systematic review of head and neck cancer quality of life assessment instruments.Oral Oncol. 2012; 48: 923-937
- Tooth loss and oral health-related quality of life: a systematic review and meta-analysis.Health Qual Life Outcomes. 2010; 8: 126
- Derivation and validation of a short-form oral health impact profile.Community Dent Oral Epidemiol. 1997; 25: 284-290
- The performance status scale for head and neck cancer patients and the functional assessment of cancer therapy-head and neck scale. A study of utility and validity.Cancer. 1996; 77: 2294-2301
- Quality of life research in head and neck cancer: a review of the current state of the science.Crit Rev Oncol Hematol. 2007; 62: 251-267
- The impact of low-level laser therapy on oral mucositis and quality of life in patients undergoing hematopoietic stem cell transplantation using the Oral Health Impact Profile and the Functional Assessment of Cancer Therapy-Bone Marrow Transplantation questionnaires.Photomed Laser Surg. 2015; 33: 357-363
- Epidemiologic trends in head and neck cancer and aids in diagnosis.Oral Maxillofac Surg Clin North Am. 2014; 26: 123-141
- Oral health status and dental care behaviours of head and neck cancer patients: a cross-sectional study in an Austrian tertiary hospital.Clin Oral Investig. 2016; 20: 1317-1327
- Dental needs in Brazilian patients subjected to head and neck radiotherapy.Braz Dent J. 2009; 20: 74-77
- The effect of preventive oral care on treatment outcomes of a cohort of oral cancer patients.Support Care Cancer. 2016; 24: 1663-1670
- Lack of osteoradionecrosis of the mandible after intensity-modulated radiotherapy for head and neck cancer: likely contributions of both dental care and improved dose distributions.Int J Radiat Oncol Biol Phys. 2007; 68: 396-402
- Oral and general health-related quality of life in patients treated for oral cancer compared to control group.Health Qual Life Outcomes. 2015; 13: 9
- Predictors of quality of life in head and neck cancer survivors up to 5 years after end of treatment: a cross-sectional survey.Support Care Cancer. 2016; 24: 2463-2472
- Quality of life in head and neck cancer patients: impact of HPV and primary treatment modality.Laryngoscope. 2014; 124: 1592-1597
- Human papillomavirus-positive oral cavity and oropharyngeal cancer patients do not have better quality-of-life trajectories.Otolaryngol Head Neck Surg. 2012; 146: 739-745
- Head and neck cancer radiation therapy with and without chemotherapy may result in decreased health-related quality of life followed by a return to baseline over a 1-year period.J Evid Based Dent Pract. 2015; 15: 25-27
- Survivorship and quality of life in head and neck cancer.J Clin Oncol. 2015; 33: 3322-3327
- Long-term quality of life after swallowing and salivary-sparing chemo-intensity modulated radiation therapy in survivors of human papillomavirus-related oropharyngeal cancer.Int J Radiat Oncol Biol Phys. 2015; 91: 925-933
Published online: August 06, 2016
Accepted: July 30, 2016
Received in revised form: July 25, 2016
Received: February 17, 2016
Supported by a grant from the Australian and New Zealand Association of Oral and Maxillofacial Surgeons (ANZAOMS).
© 2016 Elsevier Inc. All rights reserved.