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ODONTOGENIC CYST WITH EPITHELIAL DYSPLASIA: REPORT OF A RARE CASE

      Epithelial dysplasia in odontogenic cystic is a rare histopathologic finding that may progress to squamous cell carcinoma. We report the case of a female patient, 77 years old, leucoderma, non-smoker, with pain in the mandible and purulent drainage for 2 months. Panoramic x-ray revealed unilocular radiolucent lesion involving the crown of a right impacted premolar, next to 3 dental implants. The axial view of computed tomography showed rupture of the lingual cortical. Under the presumptive diagnosis of dentigerous cyst, the excisional biopsy was performed, and the impacted tooth and the implants were removed. The mandible was reinforced with titanium board and bone graft was used. Histopathologic examination revealed fragments of cystic capsule lined with epithelium with loss of maturation throughout thickness, cell pleomorphism, and hyperchromatic nuclei. There was positive staining for p53 and Ki-67. Final diagnosis was odontogenic cyst with epithelial dysplasia. After 7 months’ follow-up no recurrence was observed.
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