Although rare, ameloblastic carcinoma (AC) is one of the most common malignant tumors
occurring in the odontogenic epithelium. Evidenced-based medical guidelines for AC
are not established because AC is a rare type of cancer. However, surgery for AC is
the primary initial treatment modality. A few reports suggest that radiotherapy (RTx)
is effective for AC; however, the tumor is generally considered to be radioresistant.
Furthermore, if RTx is performed for AC, osteonecrosis may occur because most of the
ACs arise from the jaw. Here, we report a case of an older patient with maxillary
AC who had underlying medical problems and who received conventional RTx with good
outcomes. Ten years after the treatment, no major adverse event accompanying irradiation,
local recurrence, or metastasis was observed. We discuss the therapeutic effect and
usefulness of RTx on AC. As indicated by our findings, RTx for AC may represent a
definitive treatment strategy for patients with poor general conditions or those with
tumors that cannot be resected completely.
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Article info
Publication history
Published online: October 04, 2018
Accepted:
September 24,
2018
Received in revised form:
September 19,
2018
Received:
August 19,
2018
Identification
Copyright
© 2018 Elsevier Inc. All rights reserved.
