Objectives
Odontogenic tumors (ODTs) are a heterogeneous group of lesions derived from elements
of tooth-forming tissues. No detailed data on the incidence of odontogenic tumors
in the United Kingdom have been published. The aim of this study was to retrospectively
describe the range and incidence of odontogenic tumors from 1992 to 2016 in a single
specialist unit and to compare this population with others.
Study Design
By using the Oral and Maxillofacial Pathology database, Sheffield (UK), we included
both local and referred consultation cases. A proportion of diagnoses were reclassified
in accordance with the 2017 World Health Organization classification.
Results
In total, 559 odontogenic tumors were diagnosed. Overall, the most common lesions
were ameloblastoma (196 [33.8%]), odontoma (148 [25.5%]), and odontogenic myxoma (37
[6.3%]), but this varied between local and referral case populations, with odontomas
being most common in the local population (43%). The sites affected and the gender
and age of patients were similar to other Western populations. Malignant ODTs comprised
33 cases (5.7%), of which 9 (27.3%) were ameloblastic carcinoma. The majority of the
malignant ODTs comprised referral cases.
Conclusions
Here, we present the first detailed data on ODTs within a UK population, and the pattern
of incidence from the local population is similar to other Western populations. The
exceptional rarity of malignant ODTs emphasizes the need for specialist centers for
their treatment to gain diagnostic experience.
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Article info
Publication history
Published online: October 04, 2018
Accepted:
September 23,
2018
Received in revised form:
September 10,
2018
Received:
May 14,
2018
Identification
Copyright
© 2018 Elsevier Inc. All rights reserved.
