Introduction
Contact stomatitis (CS) is an inflammatory reaction of the oral mucosa induced by
contact with an irritant, such as menthol and cinnamon compounds. We are reporting
2 cases of CS related to the use of kolanut, a caffeine-containing nut of evergreen
trees.
Case Description
Case 1 was a 22-year-old man with history of chewing kolanut for the past 10 years;
he presented with a grayish-white, velvety, leukoplakia-like plaque with ill-defined
borders in the mandibular anterior facial vestibule and extending to the lower labial
mucosa. The patient had never consumed tobacco products or alcohol before. Histopathologic
analysis revealed hyperparakeratosis with otherwise normal epithelium. The patient
continued kolanut consumption with persistent oral changes. Case 2 was a 29-year-old
man with history of chewing kolanut for the past 2 years; he presented with extensive,
diffuse, white, leukoplakia-like plaques on the anterior maxillary and all mandibular
gingiva and vestibule, with epithelial desquamation and erosive patches. The patient
reported smoking 30 cigarettes per day for the last 11 year. Following cessation of
kolanut use, the leukoplakia-like lesion resolved with persistent erythema.
Conclusions
This is the first report of histopathologic characterization of CS associated with
the use of kolanut, which is believed to be reactive in nature with unknown premalignant
potential.
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Article info
Publication history
Published online: May 14, 2020
Accepted:
April 4,
2020
Received in revised form:
March 28,
2020
Received:
March 7,
2020
Identification
Copyright
© 2020 Elsevier Inc. All rights reserved.
