Clinicopathologic Conference Section| Volume 133, ISSUE 1, P3-7, January 2022

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Multiple painful ulcerated lesions in a 73-year-old patient

      A 73-year-old White male presented to the clinic for evaluation of multiple painful oral ulcers. The patient had noticed these ulcers 1.5 months earlier. He reported a gradual increase in size, specifically of an ulcer on the right lateral tongue which was associated with pain and difficulty in eating. Blister formation preceded the development of these ulcers, and he had not experienced similar issues at any time before. He denied ulcers or bullous lesions on the skin or other mucosal areas of the body. His medical history was significant for acute myeloid leukemia (AML), which had been diagnosed a month earlier; gout; and high blood pressure. The patient also reported a recent unexplained 13 lb weight loss. The list of medications included naproxen, gabapentin, ranitidine, valsartan, and atenolol. There was a remote history of smoking 50 years prior for 6 months and occasional alcohol consumption.
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