If you don't remember your password, you can reset it by entering your email address and clicking the Reset Password button. You will then receive an email that contains a secure link for resetting your password
If the address matches a valid account an email will be sent to __email__ with instructions for resetting your password
Corresponding author: Ana Gabriela Costa Normando, DDS, MSc, Oral Diagnosis Department Piracicaba Dental School, University of Campinas, (Unicamp) Av. Limeira, 901, Bairro Areão Piracicaba-SP, 13414-903, Brazil
A 66-year-old male patient was referred with a chief complaint of an asymptomatic
ulcerated nodule on the tongue with 2 months of evolution. The patient’s medical history
included hypertension; multiple basal cell carcinomas on the skin, which were surgically
treated; and prostate cancer, which was still being treated with radiotherapy. The
patient also reported the use of antiandrogens. Information on tobacco or alcohol
consumption was not elicited. Extraoral examination revealed facial lesions characterized
by areas of hypo- and hyperpigmentation of the skin, actinic lentigines, actinic keratosis,
and actinic cheilitis (Figure 1A-1D). Ocular alterations, including hyperemia, loss of eyelashes, and pterygium, were
also observed. Intraoral examination revealed a single oval-shaped nodule, with a
distally discrete ulcerated area presenting slightly elevated white edges with granular
surface and an erythematous center, located in the left apex of the tongue. The entire
lesion presented a fibrous consistency and well-defined margins and measured approximately
1.0 × 0.5 cm (Figure 2). Clinical assessment of cervical lymph nodes did not show evidence of regional metastasis.
Fig. 1Extraoral findings of the case. (A-C) Multiple skin lesions on both facial sides, extending to the neck and scalp, which
included hyper- and hypopigmented macules, actinic lentigines, and actinic keratosis.
(D) Blurred interface between the vermillion mucosa and the cutaneous part of the lips.
Fig. 2Clinical features of the intraoral lesion. (A) Anteriorly, an oval-shaped nodule presenting an area with elevated white edges and
erythematous center. (B) In a high-power view, 2 distinct areas of the lesion are observed, as well as its
well-defined margins.
