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A 38-year-old female patient was referred to our department of oral pathology with
a chief complaint of a painless and nonhealing “hole in her palate” with an evolution
time of 30 days. Clinical examination revealed an area of necrosis affecting the left
posterior region of the hard palate (Figure 1), and imaging examinations demonstrated no sign of oronasal communication. No palpable
cervical lymph node was found. The patient reported a 3-year history of cigarette
smoking, approximately 40 cigarettes per day, and she presented with a nonproductive
cough lasting for 6 months, considered a complication of the smoking habit. No other
relevant medical history that could have influenced the development of necrosis in
the region, such as radiotherapy treatment or use of bisphosphonates, was reported.
Fig. 1Initial appearance of the oral injury, presenting clinically as a necrotic ulcer.