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Diagnostic value of magnetic resonance imaging in cervical lymph node metastasis of oral squamous cell carcinoma

  • Author Footnotes
    ⁎⁎ Resident.
    Yuxin Wang
    Footnotes
    ⁎⁎ Resident.
    Affiliations
    Department of Oral and Maxillofacial-Head and Neck Oncology, Beijing Stomatological Hospital, Capital Medical University, Beijing, China
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  • Author Footnotes
    † Attending Doctor.
    Minghui Mao
    Footnotes
    † Attending Doctor.
    Affiliations
    Department of Oral and Maxillofacial-Head and Neck Oncology, Beijing Stomatological Hospital, Capital Medical University, Beijing, China
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  • Author Footnotes
    ‡ Attending Doctor.
    Jinzhong Li
    Footnotes
    ‡ Attending Doctor.
    Affiliations
    Department of Oral and Maxillofacial-Head and Neck Oncology, Beijing Stomatological Hospital, Capital Medical University, Beijing, China
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  • Author Footnotes
    § Associate Professor.
    Zhien Feng
    Footnotes
    § Associate Professor.
    Affiliations
    Department of Oral and Maxillofacial-Head and Neck Oncology, Beijing Stomatological Hospital, Capital Medical University, Beijing, China
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  • Author Footnotes
    || Professor.
    Lizheng Qin
    Footnotes
    || Professor.
    Affiliations
    Department of Oral and Maxillofacial-Head and Neck Oncology, Beijing Stomatological Hospital, Capital Medical University, Beijing, China
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  • Author Footnotes
    ¶ Department Head.
    Zhengxue Han
    Correspondence
    Corresponding author. Zhengxue Han, MD, PhD, Department of Oral & Maxillofacial-Head & Neck Oncology, Beijing Stomatological Hospital, Capital Medical University, No. 4 Tian Tan Xi Li, Dongcheng District, Beijing 100050, PR China. Tel.: 86-10-57099152; Fax: 86-10-57099151.
    Footnotes
    ¶ Department Head.
    Affiliations
    Department of Oral and Maxillofacial-Head and Neck Oncology, Beijing Stomatological Hospital, Capital Medical University, Beijing, China
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  • Author Footnotes
    ⁎⁎ Resident.
    † Attending Doctor.
    ‡ Attending Doctor.
    § Associate Professor.
    || Professor.
    ¶ Department Head.
Published:November 07, 2021DOI:https://doi.org/10.1016/j.oooo.2021.10.024

      Abstract

      Objective

      To investigate the correlation between magnetic resonance imaging (MRI) characteristics of cervical lymph nodes and the pathologically confirmed status of cervical lymph node metastasis (LNM) in oral squamous cell carcinoma (OSCC) and to provide imaging evaluation parameters for the clinical diagnosis of cervical lymph node status in OSCC.

      Study Design

      In a retrospective analysis, 79 patients who were first pathologically diagnosed with OSCC were included. The MRI-derived imaging parameters of the cervical lymph nodes were evaluated and the pathological status of lymph nodes in neck dissection specimens was reviewed. The relationship between the imaging parameters and cervical LNM was analyzed.

      Results

      The MRI-derived imaging parameters of 4,419 lymph nodes were evaluated and the pathological status of 2,463 lymph nodes was reviewed. The MRI-derived shortest axial diameter (SAD) and unclear boundary of the cervical lymph node were significantly related to LNM. The cutoff value of SAD that enabled identification of LNM was 3.6 mm and was 4.2 and 4.1 mm for the prediction of OS and DSS, respectively.

      Conclusions

      The MRI-derived parameters SAD and unclear boundary of the cervical lymph node correlated with LNM in OSCC. MRI-derived SAD larger than 3 mm warrants simultaneous neck dissection at initial surgery.

      Keywords

      Abbreviations:

      LAD (longest axial diameter), SAD (shortest axial diameter), PCB (percentage of lymph nodes with clear boundary), PCS (percentage of lymph nodes with consistent internal signals), LNM (lymph node metastasis), MRI (magnetic resonance imaging)
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