Admission C-Reactive Protein, WBC Count, Glucose, and Body Temperature in Severe Odontogenic Infections: A Retrospective Study Using Severity Scores

Published:November 11, 2021DOI:

      Structured Abstract


      The purpose of this study is to determine whether various serum marker levels [C-reactive protein (CRP), white blood cell (WBC) count, glucose] or body temperature at admission are associated with severity of odontogenic infections.

      Study Design

      This retrospective chart review of patients admitted to the hospital for treatment of severe odontogenic infections (SOIs) over a five-year period (2016- 2020) assigned patients with a severity score (SS) of greater than or equal to five to Group A and those with a SS of less than five to Group B. Serum marker levels and temperature at admission were collected, and comparisons between Group A and Group B were conducted for serum marker levels and body temperature at admission using two sample t-tests.


      The mean serum CRP and temperature at admission between the two groups was not statistically significant (p > 0.05). The mean WBC count and serum glucose at admission between the two groups was statistically significant (p = 0.001 and p = 0.036, respectively).


      This study demonstrates that serum glucose and WBC at admission are significantly higher in patients with more severe SOIs. In addition, serum CRP and body temperature at admission are not adequate prognostic indicators of odontogenic infection severity.
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