Objective
The buccal mucosa graft (BMG) is the standard graft for reconstructive urology, but
management of the donor site remains under debate. The authors compared postoperative
oral adverse outcomes between management methods (closure, nonclosure, or xenograft-assisted
closure).
Study Design
A retrospective cohort study was conducted, enrolling patients treated at Harborview
Medical Center, Seattle, Washington. The patients had a history of urethroplasty using
a unilateral BMG, and the primary outcome variables were postoperative oral adverse
outcomes, defined as subjective changes in mouth opening, smile, chewing, speech,
intraoral bleeding, paresthesia, trismus, and infection. Multivariate and regression
analyses were performed.
Results
The sample was composed of 137 patients (95% male; mean age, 48 years). The mean surface
areas of the BMG for closure, nonclosure, and xenograft were 1059, 1178, and 1228
mm2, respectively. Thirty-four patients completed the survey (7 closure, 17 nonclosure,
and 10 xenograft). Multiple linear regression showed a significant difference between
the 3 groups with respect to patient-reported chewing ability and trismus favoring
xenograft at larger graft sizes (P < .01).
Conclusions
Xenograft-assisted closure may reduce long-term oral adverse outcomes associated with
trismus and subjective changes in chewing, mouth opening, speaking, and smiling with
larger grafts. In addition, limited postoperative patient education for oral rehabilitation
exercises was noted.
Abbreviations:
BMG (Buccal Mucosa Graft)To read this article in full you will need to make a payment
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Article info
Publication history
Published online: March 28, 2022
Accepted:
March 24,
2022
Received in revised form:
February 21,
2022
Received:
October 26,
2021
Identification
Copyright
© 2022 Elsevier Inc. All rights reserved.
