This study reports 9 additional tongue hamartomas in children paired with a literature
review. A retrospective analysis was performed from 3 Oral Pathology laboratories.
Additionally, a literature review was conducted through 5 electronic databases and
gray literature. A total of 9 cases were identified in the retrospective analysis.
Females outnumbered males with a ratio of 1.25:1. The age of presentation ranged from
2 weeks to 7 years. The posterior dorsum tongue was the most affected subsite (n = 4). One case was seen in a patient with oro-facial-digital syndrome, 2 cases in
patients with cleft palates, and one case with an encephalocele. The most common predominant
component was salivary gland tissue (n = 4). A literature search included 79 pediatric patients presenting with 95 tongue
hamartomas. A slight female (n = 47) predilection was observed, with ages varying from 15 hours to 19 years. The
posterior tongue dorsum (n = 31) was the most affected site. Seven cases were seen in association with syndromes.
The most common predominant component was smooth muscle (n = 35). Although hamartomas are rare in the oral cavity, they should be considered
in the differential diagnosis of masses involving the posterior tongue dorsum in children.
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Article info
Publication history
Published online: June 30, 2022
Accepted:
June 20,
2022
Received in revised form:
June 10,
2022
Received:
November 18,
2021
Identification
Copyright
© 2022 Elsevier Inc. All rights reserved.
