Mycosis fungoides (MF) is a rare cutaneous T-cell lymphoma (CTCL) with significant
morbidity and mortality rates. Involvement of MF in the oral cavity is uncommon, often
follows cutaneous involvement, and is usually associated with a poor prognosis. Herein,
we describe a case of a 72-year-old White male with biopsy-proven oral T-cell lymphoma
(TCL) in the setting of MF with systemic disease progression. Mycosis fungoides with
oral involvement can often prove challenging to diagnose and manage. Thorough medical
history intake and clinical examination supported by histopathologic and immunohistochemical
analysis are imperative because delay in the diagnosis can lead to disease progression.
To read this article in full you will need to make a payment
Purchase one-time access:
Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online accessOne-time access price info
- For academic or personal research use, select 'Academic and Personal'
- For corporate R&D use, select 'Corporate R&D Professionals'
Subscribe:
Subscribe to Oral Surgery, Oral Medicine, Oral Pathology and Oral RadiologyAlready a print subscriber? Claim online access
Already an online subscriber? Sign in
Register: Create an account
Institutional Access: Sign in to ScienceDirect
REFERENCES
- Mycosis fungoides and Sézary syndrome: an update.Hematol Oncol Clin North Am. 2019; 33: 103-120
- Mycosis fungoides.in: Carter JB Goyal A Duncan LM Atlas of Cutaneous Lymphomas: Classification and Differential Diagnosis. 1st ed. Springer Science+Business Media, Berlin, Germany2015: 139-152
- Mycosis fungoides: developments in incidence, treatment and survival.J Eur Acad Dermatol Venereol. 2020; 34: 2288-2294
- Cutaneous lymphoproliferative diseases and related disorders.in: Calonje E Brenn T Lazar A Billings SD McKee's Pathology of the Skin: With Clinical Correlations. 5th ed. Elsevier, Edinburgh, Scotland2020: 1403-1519
- Mycosis fungoides involving head and neck mucosal sites: review of the literature.Appl Rad Onco. 2017; 6: 11-19
- Large cell transformation of oral mycosis fungoides.Head Neck Pathol. 2018; 12: 247-251
- Oral and Maxillofacial Pathology.Saunders, Philadelphia, PA2009
- Oral involvement of cutaneous T-cell lymphoma.Dermatol Online J. 2017; 23 (13030/qt1xn9q4n9)
- Oral manifestations of cutaneous T-cell lymphoma. A report of eight cases. Oral Surg Oral Med Oral.Pathol. 1993; 75: 700-705
- Characteristics of oral and paraoral malignant lymphoma: a population-based review of 361 cases.Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2001; 92: 519-525
- Non-Hodgkin’s lymphomas of head and neck extranodal sites.Int J Radiat Oncol Biol Phys. 1985; 11: 357-364
- Oral manifestations of lymphoma: a systematic review.Ecancermedicalscience. 2016; 10: 665
- Extranodal NK/T cell lymphoma with destruction of the uvulae: a case report.Iran J Otorhinolaryngol. 2017; 29: 101-108
- Mycosis fungoides involving the oral cavity.Australas Radiol. 2002; 46: 336-339
- Management strategies for mycosis fungoides in India.Indian J Dermatol. 2017; 62: 137-141
- Survival in mycosis fungoides and Sezary syndrome: how can we predict outcome?.J Invest Dermatol. 2020; 140: 281-283
Article info
Publication history
Published online: December 22, 2022
Accepted:
December 15,
2022
Received in revised form:
November 10,
2022
Received:
September 8,
2022
Identification
Copyright
© 2022 Elsevier Inc. All rights reserved.