Xerostomia, Reduced Salivary Flow, and Oral Burning: Associations from a Cross-Sectional Study

Published:January 03, 2023DOI:



      : Determine the association between xerostomia, salivary flow, and oral burning.

      Study Design

      : A cross-sectional retrospective study involving consecutive patients with an oral burning complaint during a 6-year period. Treatments including a dry mouth management protocol (DMP) along with other therapies were implemented. Study variables included: xerostomia, unstimulated whole salivary flow rate (UWSFR), pain intensity, and medication use. Statistical analyses included Pearson correlations, linear regression, and ANOVA.


      : Among the 124 patients meeting the inclusion criteria, 99 were female, mean age of 63.1 (range 26 to 86) years. Baseline UWSFR was low (0.24 ± 0.29 mL/min) and 46% experienced hyposalivation (< 0.1 mL/min). Xerostomia was reported by 77.7% and 82.8% had coexistence of xerostomia and hyposalivation. DMP resulted in significant pain reduction between visits (p < 0.001).


      Hyposalivation and xerostomia were highly prevalent in patients with oral burning. A DMP proved beneficial to these patients.


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