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This research did not receive any specific grant from funding agencies in the public, commercial, or not-for-profit sectors.
Declaration of Competing Interest
The authors have no relevant financial or non-financial interests to disclose.
The content of this study was partially presented previously at MASCC/ISOO 2022 Annual meeting. Additionally, a previous version of this study is also available as a preprint on Research Square platform - DOI: 10.21203/rs.3.rs-1661856/v1.
Statement of Clinical Relevance
EGFR inhibitors such as panitumumab have been associated with changes in oral mucosa. Although panitumumab-containing regimes seem generally well accepted, oral lesions among other adverse events associated with this targeted agent may affect the tolerability of patients undergoing cancer treatment.
The authors would like to thank Dr. Jorge Sabbaga, head of gastrointestinal clinical oncology department of Instituto do Câncer do Estado de São Paulo to the research support.