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CLINICOPATHOLOGIC CONFERENCE|Articles in Press

Expansile, mandibular lesion in a pediatric patient

Published:February 13, 2023DOI:https://doi.org/10.1016/j.oooo.2023.02.005
      A 15-year-old male with no medical or surgical history was referred to the University of Texas Health Science Center at Houston Department of Oral and Maxillofacial Surgery from a community general dentist's office to evaluate an expansion and swelling of the left mandible. The patient reported “a ball in [his] jaw,” which had slowly developed over months, endorsing a subjective sensation of pressure in the mandibular left quadrant. He denied any history of pain or altered sensation. On examination, the buccal cortical bone expanded in the area of teeth #19 through #22. The teeth were non-mobile and non-tender to percussion or palpation. A cone beam computed tomography was obtained after showing a 30 × 30 × 27-mm unilocular radiolucency with scalloped borders and resorption of tooth roots #20 and #21, and displacement of teeth #19 through #22 (Fig. 1A-1C).
      Fig 1
      Fig. 1(A) Initial panoramic imaging of lesion obtained at the first appointment. (B) Axial and coronal slices from the cone beam computed tomography obtained at the first appointment. (C) Three-dimensional reconstruction from the cone beam computed tomography obtained at the first appointment.
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      REFERENCES

        • Yu YH
        • Wu JT
        • Ye J
        • Chen MX
        Radiological findings of malignant peripheral nerve sheath tumor: Reports of six cases and review of literature.
        World J Surg Oncol. 2016; 14: 142
        • Minovi A
        • Basten O
        • Hunter B
        • Draf W
        • Bockmühl U
        Malignant peripheral nerve sheath tumors of the head and neck: management of 10 cases and literature review.
        Head Neck. 2007; 29: 439-445
        • Ueda R
        • Saito R
        • Horiguchi T
        • Nakamura Y
        • Ichikizaki K
        Malignant peripheral nerve sheath tumor in the anterior skull base associated with neurofibromatosis type 1—case report.
        Neurol Med Chir (Tokyo). 2004; 44: 38-42
        • Arshi A
        • Tajudeen BA
        • St John M
        Malignant peripheral nerve sheath tumors of the head and neck: demographics, clinicopathologic features, management, and treatment outcomes.
        Oral Oncol. 2015; 51: 1088-1094
        • Murphey MD
        • Smith WS
        • Smith SE
        • Kransdorf MJ
        • Temple HT
        From the archives of the AFIP. Imaging of musculoskeletal neurogenic tumors: radiologic-pathologic correlation.
        Radiographics. 1999; 19: 1253-1280
        • Trout E
        • Patel A
        • Golchian D
        Epithelioid malignant peripheral nerve sheath tumor.
        Appl Radiol. 2018; 47: 24-26
        • Ducatman BS
        • Scheithauer BW
        • Piepgras DG
        • ReimanHM Ilstrup DM
        Malignant peripheral nerve sheath tumors. A clinicopathologic study of 120 cases.
        Cancer. 1986; 57: 2006-2021
        • van Noesel MM
        • Orbach D
        • Brennan B
        • et al.
        Outcome and prognostic factors in pediatric malignant peripheral nerve sheath tumors: an analysis of the European Pediatric Soft Tissue Sarcoma Group (EpSSG) NRSTS-2005 prospective study.
        Pediatr Blood Cancer. 2019; 66: e27833
        • Oztürk O
        • Tutkun A
        A case report of a malignant peripheral nerve sheath tumor of the oral cavity in neurofibromatosis type 1.
        Case Rep Otolaryngol. 2012; 2012936735
        • Ramalingam WV
        • Nair S
        • Mandal G
        Malignant peripheral nerve sheath tumor of the oral cavity.
        J Oral Maxillofac Surg. 2012; 70: e581-e585
        • Sham ME
        • Ghorpade Shetty A
        • Hari S
        • Vinay
        Malignant peripheral nerve cell tumour.
        J Maxillofac Oral Surg. 2010; 9: 68-71
        • Zakhary I
        • Elsalanty M
        • Ishag I
        • et al.
        Malignant peripheral nerve sheath tumor of mandible.
        J Craniofac Surg. 2011; 22: 762-766
        • Arruda JA
        • Álvares P
        • Silva L
        • et al.
        A rare malignant peripheral nerve sheath tumor of the maxilla mimicking a periapical lesion.
        Case Rep Dent. 2016; 20164101423
        • Cunha JLS
        • Tomo S
        • de Paiva Gomes Fernandes EK
        • et al.
        Primary intraosseous malignant peripheral nerve sheath tumor of the mandible: an unusual presentation mimicking a benign lesion.
        Oral Oncol. 2021; 120105266
        • Hujala K
        • Martikainen P
        • Minn H
        • Grénman R
        Malignant nerve sheath tumors of the head and neck: four case studies and review of the literature.
        Eur Arch Otorhinolaryngol. 1993; 250: 379-382
        • Mullins BT
        • Hackman T
        Malignant peripheral nerve sheath tumors of the head and neck: a case series and literature review.
        Case Rep Otolaryngol. 2014; 2014368920
        • Ma C
        • Ow A
        • Shan OH
        • et al.
        Malignant peripheral nerve sheath tumours in the head and neck region: retrospective analysis of clinicopathological features and treatment outcomes.
        Int J Oral Maxillofac Surg. 2014; 43: 924-932
        • Gazendam AM
        • Popovic S
        • Munir S
        • Parasu N
        • Wilson D
        • Ghert M
        Synovial sarcoma: a clinical review.
        Curr Oncol. 2021; 28: 1909-1920
        • Cai Z
        • Tang X
        • Liang H
        • Yang R
        • Yan T
        • Guo W
        Prognosis and risk factors for malignant peripheral nerve sheath tumor: a systematic review and meta-analysis.
        World J Surg Oncol. 2020; 18: 257