The aim of the study was to assess the usefulness of using a bovine bone substitute material in the treatment of cystic lesions in the jaw with a maximum diameter of < 4 cm.
Material and methods
In this prospective, randomised, single-blind intervention study of 116 patients, 61 underwent cystectomy with subsequent filling of the defect using a bovine xenograft, and 55 underwent cystectomy alone. Volumetric measurement of the cysts was performed preoperatively and 6 and 12 months postoperatively using the available digital volume tomography (DVT) data sets. Follow-up appointments were made after 14 days and 1, 3, 6 and 12 months postoperatively.
Almost complete regeneration was seen in both treatment groups within 12 months, with no significant difference in absolute volume loss between the two groups (p = .521). Examination 14 days after surgery revealed a tendency for more wound healing disorders with the use of a bone substitute (p = .077). It was no longer possible to detect any further differences in later examinations.
The use of a bovine bone substitute material has no radiologically measurable advantage over cystectomy alone without defect filling, with regard to bone regeneration. In addition, there was a tendency for more wound healing disorders to occur in the bone substitute group.
To read this article in full you will need to make a payment
Purchase one-time access:Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
One-time access price info
- For academic or personal research use, select 'Academic and Personal'
- For corporate R&D use, select 'Corporate R&D Professionals'
Subscribe:Subscribe to Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
Already a print subscriber? Claim online access
Already an online subscriber? Sign in
Register: Create an account
Institutional Access: Sign in to ScienceDirect
Accepted: February 17, 2023
Received in revised form: February 17, 2023
Received: December 18, 2022
Publication stageIn Press Journal Pre-Proof
Sources of Support: only institutional support, no conflict of interest
© 2023 Elsevier Inc. All rights reserved.