ABSTRACT
Objective
The aim of the study was to assess the usefulness of using a bovine bone substitute
material in the treatment of cystic lesions in the jaw with a maximum diameter of
< 4 cm.
Material and methods
In this prospective, randomised, single-blind intervention study of 116 patients,
61 underwent cystectomy with subsequent filling of the defect using a bovine xenograft,
and 55 underwent cystectomy alone. Volumetric measurement of the cysts was performed
preoperatively and 6 and 12 months postoperatively using the available digital volume
tomography (DVT) data sets. Follow-up appointments were made after 14 days and 1,
3, 6 and 12 months postoperatively.
Results
Almost complete regeneration was seen in both treatment groups within 12 months, with
no significant difference in absolute volume loss between the two groups (p = .521).
Examination 14 days after surgery revealed a tendency for more wound healing disorders
with the use of a bone substitute (p = .077). It was no longer possible to detect
any further differences in later examinations.
Conclusion
The use of a bovine bone substitute material has no radiologically measurable advantage
over cystectomy alone without defect filling, with regard to bone regeneration. In
addition, there was a tendency for more wound healing disorders to occur in the bone
substitute group.
Keywords
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Article info
Publication history
Accepted:
February 17,
2023
Received in revised form:
February 17,
2023
Received:
December 18,
2022
Publication stage
In Press Journal Pre-ProofFootnotes
Sources of Support: only institutional support, no conflict of interest
Identification
Copyright
© 2023 Elsevier Inc. All rights reserved.
