Papillary thyroid carcinoma (PTC) and cribriform adenocarcinoma of the tongue and minor salivary glands (CATMSG) are head and neck tumors that share many histologic features and can be difficult to differentiate based on morphology alone. We report a case of a tongue base mass initially diagnosed as CATMSG, which after further ancillary studies was found to be metastatic PTC. Due to the significant differences in patient management, we review the literature and recommend routine immunohistochemical testing with thyroid transcription factor-1 and thyroglobulin.
Abbreviations:PTC (CATMSG), TTF-1 (thyroglobulin)
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Accepted: March 6, 2023
Received in revised form: March 2, 2023
Received: July 18, 2022
Publication stageIn Press Journal Pre-Proof
© 2023 Published by Elsevier Inc.