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Clinicopathologic Conference
A submucous yellow nodule of the fornix
A 47-year-old white female patient was referred to the outpatient Oral Medicine Clinic of the São Paulo State University (UNESP), School of Dentistry, Araçatuba, due to a nodular lesion in the lower lip mucosa with 10-year evolution. On anamnesis, the patient denied harmful habits and previous trauma or infection in the region of the lesion. Extraoral examination showed no abnormalities. Intraoral examination revealed a painless submucosal yellow rounded nodule measuring approximately 1 × 1 cm with A smooth surface and fibrous consistency in the midline of the lower fornix region (Figure 1).Intraoral mass, extraoral suppuration, and jaw lesions
A 77-year-old African American man with a 1-year history of an asymptomatic intraoral mass and facial edema was referred by his physician for specialized oral medicine evaluation at our department. His medical condition pointed to systemic arterial hypertension controlled with medications. His blood test results indicated elevated creatinine and urea (1.64 mg/dL and 80 mg/dL, respectively). Additionally, the patient's medical history did not indicate any antiresorptive or other drug that could alter bone remodeling, as well as radiotherapy in the head and neck region.An ulcerated nodule on the tip of the tongue of a patient with skin lesions
A 66-year-old male patient was referred with a chief complaint of an asymptomatic ulcerated nodule on the tongue with 2 months of evolution. The patient’s medical history included hypertension; multiple basal cell carcinomas on the skin, which were surgically treated; and prostate cancer, which was still being treated with radiotherapy. The patient also reported the use of antiandrogens. Information on tobacco or alcohol consumption was not elicited. Extraoral examination revealed facial lesions characterized by areas of hypo- and hyperpigmentation of the skin, actinic lentigines, actinic keratosis, and actinic cheilitis (Figure 1A-1D).Granulomatous ulceration of the palate
A 55-year-old white man, a rural worker who did not smoke or consume alcohol, was referred to the oral medicine outpatient clinic of the School of Dentistry, São Paulo State University (UNESP), (Araçatuba, Brazil), for an extensive lesion in the palate; the lesion had evolved over a period of 3 years. In anamnesis, the patient reported that 9 years before he presented to our clinic, the ulcerated and painful facial skin lesions with fast evolution had been diagnosed as pyoderma gangrenosum, which was treated with 30 sessions of hyperbaric oxygen therapy.A chronic oral ulcerative eruption
A 38-year-old, white, male patient, who worked as a bricklayer, was referred for evaluation of multiple linear painful ulcers with erythematous borders, extending to a painless small nodule in the buccal mucosa. The patient reported intense and intermittent burning sensation and pain in the right buccal mucosa, which had started suddenly about a month earlier, causing difficulty in swallowing. After 2 weeks without relief, he sought aid at an emergency service, where he was treated with antibiotics for 7 days without success.
